diff --git a/app/src/main/java/com/termux/app/TermuxApplication.java b/app/src/main/java/com/termux/app/TermuxApplication.java
index bf088758..d844c652 100644
--- a/app/src/main/java/com/termux/app/TermuxApplication.java
+++ b/app/src/main/java/com/termux/app/TermuxApplication.java
@@ -4,16 +4,20 @@ import android.app.Application;
 import android.content.Context;
 
 import com.termux.am.Am;
+import com.termux.shared.errors.Error;
 import com.termux.shared.logger.Logger;
 import com.termux.shared.shell.LocalSocketListener;
 import com.termux.shared.termux.TermuxConstants;
 import com.termux.shared.termux.crash.TermuxCrashUtils;
+import com.termux.shared.termux.file.TermuxFileUtils;
 import com.termux.shared.termux.settings.preferences.TermuxAppSharedPreferences;
 import com.termux.shared.termux.settings.properties.TermuxAppSharedProperties;
 import com.termux.shared.termux.theme.TermuxThemeUtils;
 
 public class TermuxApplication extends Application {
 
+    private static final String LOG_TAG = "TermuxApplication";
+
     public void onCreate() {
         super.onCreate();
 
@@ -33,6 +37,21 @@ public class TermuxApplication extends Application {
         // Set NightMode.APP_NIGHT_MODE
         TermuxThemeUtils.setAppNightMode(properties.getNightMode());
 
+        // Check and create termux files directory. If failed to access it like in case of secondary
+        // user or external sd card installation, then don't run files directory related code
+        Error error = TermuxFileUtils.isTermuxFilesDirectoryAccessible(this, true, true);
+        if (error != null) {
+            Logger.logErrorExtended(LOG_TAG, "Termux files directory is not accessible\n" + error);
+        } else {
+            Logger.logInfo(LOG_TAG, "Termux files directory is accessible");
+
+            error = TermuxFileUtils.isAppsTermuxAppDirectoryAccessible(true, true);
+            if (error != null) {
+                Logger.logErrorExtended(LOG_TAG, "Create apps/termux-app directory failed\n" + error);
+                return;
+            }
+        }
+
         if (LocalSocketListener.tryEstablishLocalSocketListener(this, (args, out, err) -> {
             try {
                 new Am(out, err, this).run(args);
diff --git a/termux-shared/src/main/java/com/termux/shared/termux/TermuxConstants.java b/termux-shared/src/main/java/com/termux/shared/termux/TermuxConstants.java
index 68ec885c..d400e693 100644
--- a/termux-shared/src/main/java/com/termux/shared/termux/TermuxConstants.java
+++ b/termux-shared/src/main/java/com/termux/shared/termux/TermuxConstants.java
@@ -11,7 +11,7 @@ import java.util.Formatter;
 import java.util.List;
 
 /*
- * Version: v0.39.0
+ * Version: v0.40.0
  * SPDX-License-Identifier: MIT
  *
  * Changelog
@@ -216,10 +216,10 @@ import java.util.List;
  *      - Added `TERMUX_PROPERTIES_FILE_PATHS_LIST` and `TERMUX_FLOAT_PROPERTIES_FILE_PATHS_LIST`.
  *
  * - 0.34.0 (2021-10-26)
- *  - Move `RESULT_SENDER` to `com.termux.shared.shell.command.ShellCommandConstants`.
+ *      - Move `RESULT_SENDER` to `com.termux.shared.shell.command.ShellCommandConstants`.
  *
  * - 0.35.0 (2022-01-28)
- *  - Add `TERMUX_APP.TERMUX_ACTIVITY.EXTRA_RECREATE_ACTIVITY`.
+ *      - Add `TERMUX_APP.TERMUX_ACTIVITY.EXTRA_RECREATE_ACTIVITY`.
  *
  * - 0.36.0 (2022-03-10)
  *      - Added `TERMUX_APP.TERMUX_SERVICE.EXTRA_RUNNER` and `TERMUX_APP.RUN_COMMAND_SERVICE.EXTRA_RUNNER`
@@ -233,6 +233,9 @@ import java.util.List;
  * - 0.39.0 (2022-03-18)
  *      - Added `TERMUX_APP.TERMUX_SERVICE.EXTRA_SESSION_NAME`, `TERMUX_APP.RUN_COMMAND_SERVICE.EXTRA_SESSION_NAME`,
  *          `TERMUX_APP.TERMUX_SERVICE.EXTRA_SESSION_CREATE_MODE` and `TERMUX_APP.RUN_COMMAND_SERVICE.EXTRA_SESSION_CREATE_MODE`.
+ *
+ * - 0.40.0 (2022-04-17)
+ *      - Added `TERMUX_APPS_DIR_PATH` and `TERMUX_APP.APPS_DIR_PATH`.
  */
 
 /**
@@ -657,6 +660,11 @@ public final class TermuxConstants {
 
 
 
+    /** Termux and plugin apps directory path */
+    public static final String TERMUX_APPS_DIR_PATH = TERMUX_FILES_DIR_PATH + "/apps"; // Default: "/data/data/com.termux/files/apps"
+    /** Termux and plugin apps directory */
+    public static final File TERMUX_APPS_DIR = new File(TERMUX_APPS_DIR_PATH);
+
 
 
     /*
@@ -872,6 +880,10 @@ public final class TermuxConstants {
      */
     public static final class TERMUX_APP {
 
+        /** Termux apps directory path */
+        public static final String APPS_DIR_PATH = TERMUX_APPS_DIR_PATH + "/termux-app"; // Default: "/data/data/com.termux/files/apps/termux-app"
+
+
         /** Termux app core activity name. */
         public static final String TERMUX_ACTIVITY_NAME = TERMUX_PACKAGE_NAME + ".app.TermuxActivity"; // Default: "com.termux.app.TermuxActivity"
 
diff --git a/termux-shared/src/main/java/com/termux/shared/termux/file/TermuxFileUtils.java b/termux-shared/src/main/java/com/termux/shared/termux/file/TermuxFileUtils.java
index 79770e79..68c547dc 100644
--- a/termux-shared/src/main/java/com/termux/shared/termux/file/TermuxFileUtils.java
+++ b/termux-shared/src/main/java/com/termux/shared/termux/file/TermuxFileUtils.java
@@ -307,6 +307,24 @@ public class TermuxFileUtils {
             false, false);
     }
 
+    /**
+     * Validate if {@link TermuxConstants.TERMUX_APP#APPS_DIR_PATH} exists and has
+     * {@link FileUtils#APP_WORKING_DIRECTORY_PERMISSIONS} permissions.
+     *
+     * @param createDirectoryIfMissing The {@code boolean} that decides if directory file
+     *                                 should be created if its missing.
+     * @param setMissingPermissions The {@code boolean} that decides if permissions are to be
+     *                              automatically set.
+     * @return Returns the {@code error} if path is not a directory file, failed to create it,
+     * or validating permissions failed, otherwise {@code null}.
+     */
+    public static Error isAppsTermuxAppDirectoryAccessible(boolean createDirectoryIfMissing, boolean setMissingPermissions) {
+        return FileUtils.validateDirectoryFileExistenceAndPermissions("apps/termux-app directory", TermuxConstants.TERMUX_APP.APPS_DIR_PATH,
+            null, createDirectoryIfMissing,
+            FileUtils.APP_WORKING_DIRECTORY_PERMISSIONS, setMissingPermissions, true,
+            false, false);
+    }
+
     /**
      * Get a markdown {@link String} for stat output for various Termux app files paths.
      *